A single packaging design quickly evolves into many. One product may become available in several variants (Light, with extra vitamins, ...) and those variants all have localized versions for a global market.
See how the Dynamic Content Engine and Dynamic Content for Adobe® Illustrator® can help.
This kind of quantity is an open invitation for human errors. Last minute changes do not always make it to the designer. Updating so many instances of a package is time consuming. Translations become an absolute nightmare...
That's why content and layout should be separated. A Dynamic Content solution has a lot of advantages: